Sodium/Proton antiporter of rat liver mitochondria

Rat-liver Mitochondria and Microsomes

Work by Marinetti, Erbland & Stotz (1958) on pig-heart-cell fractions and by Macfarlane, Gray & Wheeldon (1960) on rat-liver-cell fractions have indicated that the mitochondrial and microsomal phospholipids may differ significantly in composition. In view of the results obtained by Collins (1960) and by Collins & Shotlander (1961), showing the widespread occurrence of complex amino-phospholipid...

Sulphite in Rat Liver Mitochondria

1. The mechanism of sulphite and sulphate permeation into rat liver mitochondria was investigated. 2. Extramitochondrial sulphite and sulphate elicit efflux of intramitochondrial phosphate, malate, succinate and malonate. The sulphate-dependent effluxes and the sulphite-dependent efflux of dicarboxylate anions are inhibited by butylmalonate, phenylsuccinate and mersalyl. Inhibition of the phosp...

The Effect of Resveratrol against Acrolein Toxicity in Mitochondria isolated from Rat Liver

Introduction: Acrolein is an important environmental, food and water pollutant that plays an important role in the development of several diseases. Resveratrol is a phenolic compound with antioxidant properties found in fruits such as grapes, berries and peanuts. The purpose of this study was to evaluate the protective effect of resveratrol in preventing Acrolein-induced toxicity in isolated mi...

toxicity of vanadium (v+5) on isolated rat liver mitochondria

Study of Mitochondria in Rat Liver

The electron microscope has been used to determine the weight distribution of isolated subcellular particles from normal rat liver. The following results are reported: (1) There exist at least two well defined weight populations of subcellular particles; their respective median weights are 1.3 x 10(-14) and 11 x 10(-14) gm. The lighter fraction is considered to consist of lysosomes, the heavier...